Toll‐like receptor 2 activation increases contractile responses in rat corpus cavernosum (1158.6)
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چکیده
منابع مشابه
Cavernous neurotomy causes hypoxia and fibrosis in rat corpus cavernosum.
The etiologies of erectile dysfunction (ED) after nerve-sparing radical prostatectomy have not been clearly elucidated. The aim of this study was to evaluate the effects of cavernous nerve injury on cavernous fibrosis, and to consider measures to prevent irreversible damage to the cavernous tissues. Twenty male Sprague-Dawley rats constituted the study population. The animals were divided into ...
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Molecular mechanisms of the beneficial effects of angiotensin-(1-7), Ang-(1-7), in diabetes-related complications, including erectile dysfunction, remain unclear. We examined the effect of diabetes and/or Ang-(1-7) treatment on vascular reactivity and cyclic guanosine monophosphate (cGMP) phosphodiesterase (PDE) in corpus cavernosum. Male Wistar rats were grouped as (1) control, (2) diabetic (s...
متن کاملMineralocorticoid receptor expression in human penile corpus cavernosum.
OBJECTIVES Mineralocorticoid receptor (MR) is known to play physiological and pathophysiological roles in the cardiovascular system, and MR activation directly damages these organs. The aim of this study was to evaluate the expression of MR and 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) in the human penile corpus cavernosum. METHODS MR and 11β-HSD2 expression was assayed in human peni...
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Ignoring two main characteristics of the concentration-response data, correlation between observations and presence of outliers, may lead to misleading results. Therefore the special method should be considered. In this paper in to examine the effect of phenylephrine in rat Corpus cavernosum, outlier robust nonlinear mixed estimation is used. in this study, eight different doses of phenylephrin...
متن کاملTraumatic rupture of corpus cavernosum.
Traumatic rupture of corpora cavernosa is an uncommon injury. We report a case of fractured penis in a 60 year old which was managed by immediate exploration and operative repair. Post operative recovery was uneventful with full return of erectile function.
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2014
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.28.1_supplement.1158.6